| 4+ | Slobad, Goblin Tinkerer | MTGDarksteel_069 |
| 4+ | Slobad, Goblin Tinkerer (Retro Frame) | MTGBRC_118 |
| 4+ | Slogurk, the Overslime | MTGMID_242 |
| 1 | Slogurk, the Overslime (Showcase) (Foil) | MTGMID_324F |
| 4+ | Sloppity Bilepiper | MTG40K_059 |
| 4+ | Slow Motion | MTGUrzaLegacy_042 |
| 3 | Slow Motion FOIL | MTGUrzaLegacy_042F |
| 4+ | Sludge Strider | MTGConflux_126 |
| 2 | Sludge Strider FOIL | MTGConflux_126F |
| 4+ | Sluggishness | MTGUrzaLegacy_092 |
| 3 | Sluggishness Foil | MTGUrzaLegacy_092F |
| 4+ | Sluiceway Scorpion | MTGReturntoRavnica_198 |
| 4+ | Slum Reaper | MTGReturntoRavnica_077 |
| 1 | Slum Reaper | MTGGuildKit1_052 |
| 4+ | Slumbering Tora | MTGBetrayers_161 |
| 3 | Slurrk, All-Ingesting | MTGCMR_256 |
| 1 | Slurrk, All-Ingesting (Foil) | MTGCMR_256F |
| 3 | Sly Instigator | MTGC21_032 |
| 1 | Sly Instigator (Extended Art) | MTGC21_359 |
| 4+ | Smallpox | MTGTimespiral_131 |
| 4+ | Smallpox | MTGMagic2012_108 |
| 4+ | Smallpox | MTGConspiracy_125 |
| 3 | Smallpox Foil | MTGTimespiral_131F |
| 1 | Smallpox Foil | MTGMagic2012_108F |
| 4+ | Smart Ass | MTGUnhinged_045 |
| 1 | Smash | MTGApocalypse_069 |
| 4+ | Smash | MTGRAV_143 |
| 3 | Smash | MTG10ED_235 |
| 1 | Smash (Foil) | MTGRAV_143F |
| 4+ | Smash to Smithereens | MTGShadowmoor_107 |
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